Medication Side Effects on Vision: Antihistamines, SSRIs, Diuretics, and More

Have you ever noticed your eyes feeling unusually dry after allergy season? Or perhaps your vision seems a little blurrier since starting a new prescription? Medications can perform wonders for our health—but sometimes, they bring along subtle side effects that reveal themselves through our eyes.

Our visual system is astonishingly sensitive, and because the eyes share pathways and receptors with the rest of the body, they often reflect systemic changes faster than we expect. Let’s take a whimsical yet informative peek into how certain medications might be affecting what you see.

1. Antihistamines: The Dry-Eye Culprits

Those trusty allergy pills—whether over-the-counter or prescribed—are champions at blocking histamine, the chemical responsible for sneezing and itchy eyes. But while they calm your sinuses, they can also reduce tear production.

What you might notice:

• Dryness or gritty sensation

• Redness or burning

• Blurred vision that improves with blinking

Tip: Stay hydrated and consider using preservative-free artificial tears. If you wear contact lenses, be extra mindful of dryness—it’s not you, it’s your medication.

2. SSRIs and Antidepressants: Mood Boosters, Moisture Reducers

Selective Serotonin Reuptake Inhibitors (SSRIs) can work wonders for emotional balance, but they may also reduce tear secretion and slightly affect how your pupils react to light.

Possible visual effects:

• Light sensitivity (photophobia)

• Mild focusing difficulties

• Increased dryness or irritation

Remember: never stop taking antidepressants abruptly—always consult your prescribing doctor and your optometrist if you notice visual changes.

3. Diuretics: The Water Managers

Often prescribed for high blood pressure or heart conditions, diuretics help your body eliminate excess fluid. Unfortunately, this can mean less moisture everywhere—including your eyes.

You might experience:

• Transient blurriness

• Dry, tired eyes

• Occasional burning or stinging

A humidifier in your home and regular eye lubrication can help keep your vision comfortable.

4. Corticosteroids and Other Medications to Watch

Long-term corticosteroid use—whether oral, topical, or inhaled—has been linked to cataracts and increased intraocular pressure, which can lead to glaucoma if unmonitored. Other medications that may affect your vision include:

• Isotretinoin (for acne): Dry eyes, light sensitivity

• Amiodarone (for heart rhythm): Corneal deposits, halos around lights

• Topiramate (for migraines): Sudden nearsightedness, angle-closure glaucoma (rare but serious)

A Gentle Reminder

Your eyes often whisper before they shout. If something feels “off”—blurriness, dryness, or sudden changes—don’t brush it aside. Bring it up during your next eye exam. At OC Optometry Group, we take a holistic approach to eye health, considering every detail of your medical history and medication list.

Your eyes tell a story—let’s make sure it’s a clear one.

Author

Alejandro Gallego Having joined us in 2025, Alejandro has quickly shown his adaptability and commitment. Knowing the importance of our practice as he has had several years of experience in other healthcare areas. Efforts to excellence are evident from day one. We’re excited to support him as he continues to grow within our organization.